In recent years, there has been a growing interest in the role of diet and nutrition in maintaining a healthy gut. One compound that has caught the attention of researchers and health enthusiasts alike is Sulforaphane. Derived from cruciferous vegetables like broccoli, Sulforaphane has been linked to a wide range of potential health benefits, including its impact on gut health.
In this study round-up, we'll delve into the latest research surrounding Sulforaphane and its effects on gut health, shedding light on its potential as a dietary tool for promoting a flourishing gut microbiome.
By Dr. Priyom Bose, Ph.D.
Several studies have indicated that SFN regulates inflammation pathways by inhibiting NF-ᴋB. This downregulation of pro-inflammatory cytokines is extremely important for developing and maintaining IBD.
Based on the evidence, broccoli and sprouts effectively improve gut microbiota and reduce inflammation in irritable bowel syndrome.
Sulforaphane Normalizes Intestinal Flora and Enhances Gut Barrier in Mice with BBN-Induced Bladder Cancer
Mol Nutr Food Res. 2018 Dec;62(24):e1800427.
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, has been proven to be highly effective in inhibiting cancer. The objective of this study is to investigate the potential roles of the gut microbiota in the inhibition of BBN-induced bladder cancer by SFN.
The results suggest that SFN protects against chemical-induced bladder cancer through normalising the composition of gut microbiota and repairing the physiological destruction of the gut barrier, as well as decreasing inflammation and the immune response.
Yanaka, J Clin Biochem Nutr. 2018 Jan;62(1):75-82.
This study demonstrates that intake of 20 g of broccoli sprouts, significantly enhances defecation with no side effects in healthy human subjects, and these beneficial effects appear to be induced by the protective effects of Sulforaphane in the broccoli sprouts on GI function against chronic oxidative stress from daily life.